The Society for Mucopolysaccharide Diseases (MPS Society, UK) was aware, through its work with patients and their families, that individuals with MPS Ill have a wide range of gastrointestinal (GI) conditions. This led to a multi-agency meeting between MPS Society and UK specialist clinics, which determined GI conditions are prevalent across all ages but have not usually caused major clinical concern.
Longevity of MPS Ill patients has increased over the last decades and GI symptoms may become more troublesome with age. It is unclear if they are a complication from prescribed treatments for GI symptoms, e.g. laxatives or antidiarrhoeals, or a feature of disease progression.
